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rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
BACKGROUND: In our previous report, the rt269I type versus the rt269L type in genotype C2 infection led to poor clinical outcomes and enhanced mitochondrial stress in infected hepatocytes. Here, we sought to investigate differences between the rt269L and rt269I types in mitochondrial functionality i...
Autores principales: | Choi, Yu-Min, Kim, Dong Hyun, Jang, Junghwa, Choe, Won Hyeok, Kim, Bum-Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064691/ https://www.ncbi.nlm.nih.gov/pubmed/36997871 http://dx.doi.org/10.1186/s11658-023-00440-1 |
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