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Absolute oral bioavailability and possible metabolic pathway of panduratin A from Boesenbergia rotunda extract in beagle dogs

CONTEXT: Attempts are ongoing to develop medications to fight against the COVID-19 pandemic. Our previous study revealed the in vitro anti-SARS-CoV-2 activity of fingerroot [Boesenbergia rotunda (L.) Mansf. (Zingiberaceae)] and its phytochemical, panduratin A. OBJECTIVE: To investigate the pharmacok...

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Detalles Bibliográficos
Autores principales: Boonyarattanasoonthorn, Tussapon, Kongratanapasert, Teetat, Jiso, Apisada, Techapichetvanich, Pinnakarn, Nuengchamnong, Nitra, Supannapan, Kittitach, Kijtawornrat, Anusak, Khemawoot, Phisit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064817/
https://www.ncbi.nlm.nih.gov/pubmed/36994846
http://dx.doi.org/10.1080/13880209.2023.2190777