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Extravasation of biodegradable microspheres in the rat brain

Drug development for neurological diseases is greatly impeded by the presence of the blood-brain barrier (BBB). We and others previously reported on extravasation of micrometer-sized particles from the cerebral microcirculation – across the BBB – into the brain tissue over the course of several week...

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Detalles Bibliográficos
Autores principales: van der Wijk, Anne-Eva, Georgakopoulou, Theodosia, Steendam, Rob, Zuidema, Johan, Hordijk, Peter L., Bakker, Erik N.T.P., van Bavel, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064830/
https://www.ncbi.nlm.nih.gov/pubmed/36994503
http://dx.doi.org/10.1080/10717544.2023.2194579