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Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy

AIMS: Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder that is characterized by progressive loss of myocardium that is replaced by fibro-fatty cells, arrhythmias, and sudden cardiac death. While myocardial degeneration and fibro-fatty replacement occur in specific locations, the...

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Detalles Bibliográficos
Autores principales: Boogerd, Cornelis J, Lacraz, Grégory P A, Vértesy, Ábel, van Kampen, Sebastiaan J, Perini, Ilaria, de Ruiter, Hesther, Versteeg, Danielle, Brodehl, Andreas, van der Kraak, Petra, Giacca, Mauro, de Jonge, Nicolaas, Junker, Jan Philipp, van Oudenaarden, Alexander, Vink, Aryan, van Rooij, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064846/
https://www.ncbi.nlm.nih.gov/pubmed/35576477
http://dx.doi.org/10.1093/cvr/cvac072