p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras

KRAS and TP53 mutations are frequently observed in extrahepatic biliary cancer. Mutations of KRAS and TP53 are independent risk factors for poor prognosis in biliary cancer. However, the exact role of p53 in the development of extrahepatic biliary cancer remains elusive. In this study, we found that...

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Detalles Bibliográficos
Autores principales: Nagao, Munemasa, Mizukoshi, Kenta, Nakayama, Shinnosuke, Namikawa, Mio, Hiramatsu, Yukiko, Maruno, Takahisa, Nakanishi, Yuki, Tsuruyama, Tatsuaki, Fukuda, Akihisa, Seno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064879/
https://www.ncbi.nlm.nih.gov/pubmed/36999984
http://dx.doi.org/10.18632/oncotarget.28380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064879/
https://www.ncbi.nlm.nih.gov/pubmed/36999984
http://dx.doi.org/10.18632/oncotarget.28380

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