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p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras
KRAS and TP53 mutations are frequently observed in extrahepatic biliary cancer. Mutations of KRAS and TP53 are independent risk factors for poor prognosis in biliary cancer. However, the exact role of p53 in the development of extrahepatic biliary cancer remains elusive. In this study, we found that...
Autores principales: | Nagao, Munemasa, Mizukoshi, Kenta, Nakayama, Shinnosuke, Namikawa, Mio, Hiramatsu, Yukiko, Maruno, Takahisa, Nakanishi, Yuki, Tsuruyama, Tatsuaki, Fukuda, Akihisa, Seno, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064879/ https://www.ncbi.nlm.nih.gov/pubmed/36999984 http://dx.doi.org/10.18632/oncotarget.28380 |
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