Structure of AlkB–AlkG shows details of alkane terminal C–H selectivity and functionalization

The cryo-EM structure of a natural AlkB–AlkG fusion from Fontimonas thermophila reveals the mechanistic basis for its selectivity towards, and functionalization of, alkane terminal C–H groups. AlkB contains an alkane entry tunnel and a diiron active site, and AlkG docks through electrostatic interac...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Research Briefing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064941/
https://www.ncbi.nlm.nih.gov/pubmed/37002482
http://dx.doi.org/10.1038/s41594-023-00964-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064941/
https://www.ncbi.nlm.nih.gov/pubmed/37002482
http://dx.doi.org/10.1038/s41594-023-00964-2

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