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Pharmacokinetics and Pharmacodynamics of Ruxolitinib: A Review

BACKGROUND AND OBJECTIVE: Ruxolitinib is a tyrosine kinase inhibitor targeting the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathways. Ruxolitinib is used to treat myelofibrosis, polycythemia vera and steroid-refractory graft-versus-host disease in the setting of...

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Detalles Bibliográficos
Autores principales: Appeldoorn, T. Y. J., Munnink, T. H. Oude, Morsink, L. M., Hooge, M. N. Lub-de, Touw, D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064968/
https://www.ncbi.nlm.nih.gov/pubmed/37000342
http://dx.doi.org/10.1007/s40262-023-01225-7