Glycolysis drives STING signaling to facilitate dendritic cell antitumor function

Activation of STING signaling in DCs promotes antitumor immunity. Aerobic glycolysis is a metabolic hallmark of activated DCs, but how the glycolytic pathway intersects with STING signaling in tumor-infiltrating DCs remains elusive. Here, we show that glycolysis drives STING signaling to facilitate...

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Detalles Bibliográficos
Autores principales: Hu, Zhilin, Yu, Xiaoyan, Ding, Rui, Liu, Ben, Gu, Chuanjia, Pan, Xiu-Wu, Han, Qiaoqiao, Zhang, Yuerong, Wan, Jie, Cui, Xin-Gang, Sun, Jiayuan, Zou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065062/
https://www.ncbi.nlm.nih.gov/pubmed/36821379
http://dx.doi.org/10.1172/JCI166031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065062/
https://www.ncbi.nlm.nih.gov/pubmed/36821379
http://dx.doi.org/10.1172/JCI166031

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