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Glutamate shall not pass: a mechanistic role for astrocytic O-GlcNAc transferase in stress and depression
Major depressive disorder, characterized by aberrant glutamatergic signaling in the prefrontal cortex (PFC), is a leading cause of disability worldwide. Depression is highly comorbid with metabolic disorders, but a mechanistic link is elusive. In this issue of the JCI, Fan and coauthors report that...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Clinical Investigation
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065068/ https://www.ncbi.nlm.nih.gov/pubmed/37009895 http://dx.doi.org/10.1172/JCI168662 |