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Asparagine protects pericentral hepatocytes during acute liver injury

The nonessential amino acid asparagine can only be synthesized de novo by the enzymatic activity of asparagine synthetase (ASNS). While ASNS and asparagine have been implicated in the response to numerous metabolic stressors in cultured cells, the in vivo relevance of this enzyme in stress-related p...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Demagny, Hadrien, Faure, Adrien, Pontanari, Francesca, Jalil, Antoine, Bresciani, Nadia, Yildiz, Ece, Korbelius, Melanie, Perino, Alessia, Schoonjans, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065070/
https://www.ncbi.nlm.nih.gov/pubmed/36719750
http://dx.doi.org/10.1172/JCI163508