The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis

Glucose homeostasis can be improved after bariatric surgery, which alters bile flow and stimulates gut hormone secretion, particularly FGF15/19. FGFR1 expression in AGRP-expressing cells is required for bile acids’ ability to improve glucose control. We show that the mouse Agrp gene has 3 promoter/e...

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Detalles Bibliográficos
Autores principales: Liu, Shun-Mei, Ifebi, Bruno, Johnson, Fred, Xu, Alison, Ho, Jacquelin, Yang, Yunlei, Schwartz, Gary, Jo, Young Hwan, Chua, Streamson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065075/
https://www.ncbi.nlm.nih.gov/pubmed/36787185
http://dx.doi.org/10.1172/JCI164185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065075/
https://www.ncbi.nlm.nih.gov/pubmed/36787185
http://dx.doi.org/10.1172/JCI164185

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