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The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis
Glucose homeostasis can be improved after bariatric surgery, which alters bile flow and stimulates gut hormone secretion, particularly FGF15/19. FGFR1 expression in AGRP-expressing cells is required for bile acids’ ability to improve glucose control. We show that the mouse Agrp gene has 3 promoter/e...
Autores principales: | Liu, Shun-Mei, Ifebi, Bruno, Johnson, Fred, Xu, Alison, Ho, Jacquelin, Yang, Yunlei, Schwartz, Gary, Jo, Young Hwan, Chua, Streamson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065075/ https://www.ncbi.nlm.nih.gov/pubmed/36787185 http://dx.doi.org/10.1172/JCI164185 |
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