Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression

Activation of the tyrosine kinase c-Src promotes breast cancer progression and poor outcomes, yet the underlying mechanisms are incompletely understood. Here, we have shown that deletion of c-Src in a genetically engineered model mimicking the luminal B molecular subtype of breast cancer abrogated t...

Descripción completa

Detalles Bibliográficos
Autores principales: Nandi, Ipshita, Smith, Harvey W., Sanguin-Gendreau, Virginie, Ji, Linjia, Pacis, Alain, Papavasiliou, Vasilios, Zuo, Dongmei, Nam, Stella, Attalla, Sherif S., Kim, Sung Hoon, Lusson, Sierra, Kuasne, Hellen, Fortier, Anne-Marie, Savage, Paul, Martinez Ramirez, Constanza, Park, Morag, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Muller, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065076/
https://www.ncbi.nlm.nih.gov/pubmed/36795481
http://dx.doi.org/10.1172/JCI162324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065076/
https://www.ncbi.nlm.nih.gov/pubmed/36795481
http://dx.doi.org/10.1172/JCI162324

Ejemplares similares