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O-GlcNAc transferase in astrocytes modulates depression-related stress susceptibility through glutamatergic synaptic transmission

Major depressive disorder is a common and devastating psychiatric disease, and the prevalence and burden are substantially increasing worldwide. Multiple studies of depression patients have implicated glucose metabolic dysfunction in the pathophysiology of depression. However, the molecular mechanis...

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Detalles Bibliográficos
Autores principales: Fan, Jun, Guo, Fang, Mo, Ran, Chen, Liang-Yu, Mo, Jia-Wen, Lu, Cheng-Lin, Ren, Jing, Zhong, Qiu-Ling, Kuang, Xiao-Jing, Wen, You-Lu, Gu, Ting-Ting, Liu, Jin-Ming, Li, Shu-Ji, Fang, Ying-Ying, Zhao, Cunyou, Gao, Tian-Ming, Cao, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065078/
https://www.ncbi.nlm.nih.gov/pubmed/36757814
http://dx.doi.org/10.1172/JCI160016