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Synergistic Effect of Lenvatinib and Chemotherapy in Hepatocellular Carcinoma Using Preclinical Models

PURPOSE: The current study aimed to evaluate the synergistic efficacy of lenvatinib and FOLFOX (infusional fluorouracil (FU), folinic acid, and oxaliplatin) in hepatocellular carcinoma (HCC) using patient-derived xenograft (PDX) and PDX-derived organotypic spheroid (XDOTS) models in vivo and in vitr...

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Detalles Bibliográficos
Autores principales: Wang, Mingxun, Yao, Xinfei, Bo, Zhiyuan, Zheng, Jiuyi, Yu, Haitao, Xie, Xiaozai, Lin, Zixia, Wang, Yi, Chen, Gang, Wu, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065123/
https://www.ncbi.nlm.nih.gov/pubmed/37007211
http://dx.doi.org/10.2147/JHC.S395474