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Synergistic Effect of Lenvatinib and Chemotherapy in Hepatocellular Carcinoma Using Preclinical Models
PURPOSE: The current study aimed to evaluate the synergistic efficacy of lenvatinib and FOLFOX (infusional fluorouracil (FU), folinic acid, and oxaliplatin) in hepatocellular carcinoma (HCC) using patient-derived xenograft (PDX) and PDX-derived organotypic spheroid (XDOTS) models in vivo and in vitr...
Autores principales: | Wang, Mingxun, Yao, Xinfei, Bo, Zhiyuan, Zheng, Jiuyi, Yu, Haitao, Xie, Xiaozai, Lin, Zixia, Wang, Yi, Chen, Gang, Wu, Lijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065123/ https://www.ncbi.nlm.nih.gov/pubmed/37007211 http://dx.doi.org/10.2147/JHC.S395474 |
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