CLPP inhibition triggers apoptosis in human ovarian granulosa cells via COX5A abnormality–Mediated mitochondrial dysfunction

Premature ovarian insufficiency (POI) is characterized by early loss of ovarian function before the age of 40 years. It is confirmed to have a strong and indispensable genetic component. Caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) is a key inducer of mitochondrial protein...

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Detalles Bibliográficos
Autores principales: Yuan, Xiong, Ma, Wenjie, Chen, Shuping, Wang, Huiyuan, Zhong, Chenyi, Gao, Li, Cui, Yugui, Pu, Danhua, Tan, Rongrong, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065195/
https://www.ncbi.nlm.nih.gov/pubmed/37007963
http://dx.doi.org/10.3389/fgene.2023.1141167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065195/
https://www.ncbi.nlm.nih.gov/pubmed/37007963
http://dx.doi.org/10.3389/fgene.2023.1141167

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