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Protease inhibition, in vitro antibacterial and IFD/MM-GBSA studies of ciprofloxacin-based acetanilides

In this study, we have investigated ciprofloxacin-based acetanilides for their in-vitro inhibitory study against gram +ve, -ve bacteria and serine protease activity. The compounds 4e and 4g showed excellent antibacterial activity against Bacillus subtilis with a zone of inhibition (ZI) values of 40...

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Detalles Bibliográficos
Autores principales: Akhtar, Rabia, Zahoor, Ameer Fawad, Mansha, Asim, Kamal, Shagufta, Khan, Samreen Gul, Raza, Zohaib, Ali, Kulsoom Ghulam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065284/
https://www.ncbi.nlm.nih.gov/pubmed/37000820
http://dx.doi.org/10.1371/journal.pone.0281044