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Deciphering the relational dynamics of AF-2 domain of PAN PPAR through drug repurposing and comparative simulations
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors, and their activation has been proven to treat mild liver fibrosis, reduce steatosis, inflammation, and the extrahepatic effects of chronic liver disease. Considering the significance of the PPARs, it is targeted for the treat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065303/ https://www.ncbi.nlm.nih.gov/pubmed/37000796 http://dx.doi.org/10.1371/journal.pone.0283743 |