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Deciphering the relational dynamics of AF-2 domain of PAN PPAR through drug repurposing and comparative simulations

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors, and their activation has been proven to treat mild liver fibrosis, reduce steatosis, inflammation, and the extrahepatic effects of chronic liver disease. Considering the significance of the PPARs, it is targeted for the treat...

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Detalles Bibliográficos
Autores principales: Gul, Fouzia, Parvaiz, Nousheen, Azam, Syed Sikander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065303/
https://www.ncbi.nlm.nih.gov/pubmed/37000796
http://dx.doi.org/10.1371/journal.pone.0283743