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Clinical utility of TGFB1 and its receptors (TGFBR1 and TGFBR2) in thyroid nodules: evaluation based on single nucleotide polymorphisms and mRNA analysis

OBJECTIVE: Abnormalities involving the TGFB1 gene and its receptors are common in several types of cancer and often related to tumor progression. We investigated the role of single nucleotide polymorphisms (SNP) in the susceptibility to cancer, their impact on its features, as well as the role of mR...

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Detalles Bibliográficos
Autores principales: Peres, Karina Colombera, Teodoro, Larissa, Amaral, Laís Helena Pereira, Teixeira, Elisângela Souza, Barreto, Icléia Siqueira, de Freitas, Leandro Luiz Lopes, Maximo, Valdemar, Assumpção, Lígia V. Montalli, Bufalo, Natassia Elena, Ward, Laura Sterian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065325/
https://www.ncbi.nlm.nih.gov/pubmed/33905626
http://dx.doi.org/10.20945/2359-3997000000330