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Clinical utility of TGFB1 and its receptors (TGFBR1 and TGFBR2) in thyroid nodules: evaluation based on single nucleotide polymorphisms and mRNA analysis
OBJECTIVE: Abnormalities involving the TGFB1 gene and its receptors are common in several types of cancer and often related to tumor progression. We investigated the role of single nucleotide polymorphisms (SNP) in the susceptibility to cancer, their impact on its features, as well as the role of mR...
Autores principales: | Peres, Karina Colombera, Teodoro, Larissa, Amaral, Laís Helena Pereira, Teixeira, Elisângela Souza, Barreto, Icléia Siqueira, de Freitas, Leandro Luiz Lopes, Maximo, Valdemar, Assumpção, Lígia V. Montalli, Bufalo, Natassia Elena, Ward, Laura Sterian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Endocrinologia e Metabologia
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065325/ https://www.ncbi.nlm.nih.gov/pubmed/33905626 http://dx.doi.org/10.20945/2359-3997000000330 |
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