Expanding Structural Space for Immunomodulatory Nucleic Acid Nanoparticles (Nanps) via Spatial Arrangement of Their Therapeutic Moieties

Different therapeutic nucleic acids (TNAs) can be unified in a single structure by their elongation with short oligonucleotides designed to self-assemble into nucleic acid nanoparticles (NANPs). With this approach, therapeutic cocktails with precisely controlled composition and stoichiometry of acti...

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Detalles Bibliográficos
Autores principales: Chandler, Morgan, Rolband, Lewis, Johnson, M. Brittany, Shi, Da, Avila, Yelixza I., Cedrone, Edward, Beasock, Damian, Danai, Leyla, Stassenko, Elizabeth, Krueger, Joanna K., Jiang, Jiancheng, Lee, Jeoung Soo, Dobrovolskaia, Marina A., Afonin, Kirill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065476/
https://www.ncbi.nlm.nih.gov/pubmed/37008199
http://dx.doi.org/10.1002/adfm.202205581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065476/
https://www.ncbi.nlm.nih.gov/pubmed/37008199
http://dx.doi.org/10.1002/adfm.202205581

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