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Expanding Structural Space for Immunomodulatory Nucleic Acid Nanoparticles (Nanps) via Spatial Arrangement of Their Therapeutic Moieties

Different therapeutic nucleic acids (TNAs) can be unified in a single structure by their elongation with short oligonucleotides designed to self-assemble into nucleic acid nanoparticles (NANPs). With this approach, therapeutic cocktails with precisely controlled composition and stoichiometry of acti...

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Detalles Bibliográficos
Autores principales:	Chandler, Morgan, Rolband, Lewis, Johnson, M. Brittany, Shi, Da, Avila, Yelixza I., Cedrone, Edward, Beasock, Damian, Danai, Leyla, Stassenko, Elizabeth, Krueger, Joanna K., Jiang, Jiancheng, Lee, Jeoung Soo, Dobrovolskaia, Marina A., Afonin, Kirill A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065476/ https://www.ncbi.nlm.nih.gov/pubmed/37008199 http://dx.doi.org/10.1002/adfm.202205581

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