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Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway

The stimulator of interferon genes (STING) protein is an important and promising innate immune target for tumor therapy. However, the instability of the agonists of STING and their tendency to cause systemic immune activation is a hurdle. The STING activator, cyclic di-adenosine monophosphate (CDA),...

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Detalles Bibliográficos
Autores principales: Jiang, Yu, Li, Xiyuan, Qian, Fenghui, Sun, Bingbing, Wang, Xiyuan, Zhang, Yan, Zhang, Deqiang, Geng, Meiyu, Xie, Zuoquan, Yang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065788/
https://www.ncbi.nlm.nih.gov/pubmed/37011280
http://dx.doi.org/10.34133/research.0102