High-throughput profiling of sequence recognition by tyrosine kinases and SH2 domains using bacterial peptide display

Tyrosine kinases and SH2 (phosphotyrosine recognition) domains have binding specificities that depend on the amino acid sequence surrounding the target (phospho)tyrosine residue. Although the preferred recognition motifs of many kinases and SH2 domains are known, we lack a quantitative description o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Allyson, Voleti, Rashmi, Lee, Minhee, Gagoski, Dejan, Shah, Neel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065799/
https://www.ncbi.nlm.nih.gov/pubmed/36927728
http://dx.doi.org/10.7554/eLife.82345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065799/
https://www.ncbi.nlm.nih.gov/pubmed/36927728
http://dx.doi.org/10.7554/eLife.82345

Ejemplares similares