Does the Tacrolimus Trough Level Adequately Predict Drug Exposure in Patients Requiring a High Tacrolimus Dose?

Tacrolimus (Tac) has a narrow therapeutic range. Dosing is generally targeted at Tac trough levels (C(0)), notwithstanding conflicting reports on the correlation between Tac C(0) and systemic exposure measured by the area-under-the-concentration-over-time curve (AUC). The Tac dose required to meet t...

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Detalles Bibliográficos
Autores principales: Haverals, Lien, Roosens, Laurence, Wouters, Kristien, Marquet, Pierre, Monchaud, Caroline, Massart, Annick, Abramowicz, Daniel, Hellemans, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Kidney Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065838/
https://www.ncbi.nlm.nih.gov/pubmed/37009168
http://dx.doi.org/10.1097/TXD.0000000000001439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065838/
https://www.ncbi.nlm.nih.gov/pubmed/37009168
http://dx.doi.org/10.1097/TXD.0000000000001439

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