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Hidden behind thromboinflammation: revealing the roles of von Willebrand factor in sickle cell disease pathophysiology

This review provides an update on the pathophysiology of sickle cell disease (SCD) with a particular focus on the dysregulation of the von Willebrand factor (VWF) - ADAMTS13 axis that contributes to its pathogenesis. In discussing recent developments, we hope to encourage new and ongoing discussions...

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Detalles Bibliográficos
Autores principales: Vital, Eudorah F., Lam, Wilbur A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065920/
https://www.ncbi.nlm.nih.gov/pubmed/36853830
http://dx.doi.org/10.1097/MOH.0000000000000755