Antimicrobial peptides CS-piscidin-induced cell death involves activation of RIPK1/PARP, and modification with myristic acid enhances its stability and tumor-targeting capability

Ovarian cancer (OC) is a highly lethal gynecological malignancy, often diagnosed at advanced stages with limited treatment options. Here, we demonstrate that the antimicrobial peptide CS-piscidin significantly inhibits OC cell proliferation, colony formation, and induces cell death. Mechanistically,...

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Detalles Bibliográficos
Autores principales: Li, Ning, Jiang, Xingmei, Ma, Xiaowan, Qiu, Xiaoju, Chang, HuangHuang, Qiao, Ying, Luo, Hui, Zhang, Qingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066050/
https://www.ncbi.nlm.nih.gov/pubmed/37000327
http://dx.doi.org/10.1007/s12672-023-00642-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066050/
https://www.ncbi.nlm.nih.gov/pubmed/37000327
http://dx.doi.org/10.1007/s12672-023-00642-1

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