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Convolution-based approach for modeling the paliperidone extended release and Long-Acting Injectable (LAI) PK of once-, and three-monthly products administration and for optimizing the development of new LAI products

The aim of this paper was to develop a convolution-based modeling approach for describing the paliperidone PK resulting from the administration of extended-release once-a-day oral dose, and once- and three monthly long-acting injectable products and to compare the performances of this approach to th...

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Detalles Bibliográficos
Autores principales: Gomeni, Roberto, Bressolle-Gomeni, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066107/
https://www.ncbi.nlm.nih.gov/pubmed/36484885
http://dx.doi.org/10.1007/s10928-022-09835-7