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A fully human anti-c-Kit monoclonal antibody 2G4 inhibits proliferation and degranulation of human mast cells

Given that mast cells are pivotal contributors to allergic diseases, various allergy treatments have been developed to inhibit them. Omalizumab, an anti-immunoglobulin E antibody, is a representative therapy that can alleviate allergy symptoms by inhibiting mast cell degranulation. However, omalizum...

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Detalles Bibliográficos
Autores principales: Kim, Kwang-Hyeok, Kim, Jin-Ock, Park, Sang Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066129/
https://www.ncbi.nlm.nih.gov/pubmed/36107283
http://dx.doi.org/10.1007/s11010-022-04557-3