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CALR type 1 mutations are associated with an increased incidence of myelofibrosis in young male patients

BACKGROUND: Calreticulin (CALR) mutations are commonly identified in patients with essential thrombocythaemia or myelofibrosis. CALR type 1 mutations are known to have a higher overall incidence in males but little is known about the risks of mutation subtypes on myelofibrotic change across patient...

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Detalles Bibliográficos
Autores principales: Weir, Philip, Hindley, Andrew, Catherwood, Mark, McMullin, Mary Frances
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066159/
https://www.ncbi.nlm.nih.gov/pubmed/35672563
http://dx.doi.org/10.1007/s11845-022-03047-1