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Nodal promotes colorectal cancer survival and metastasis through regulating SCD1-mediated ferroptosis resistance

Re-expression of an embryonic morphogen, Nodal, has been seen in several types of malignant tumours. By far, studies about Nodal’s role in colorectal cancer (CRC) remain limited. Ferroptosis is essential for CRC progression, which is caused by cellular redox imbalance and characterized by lipid pero...

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Detalles Bibliográficos
Autores principales: Wu, Tianqi, Wan, Jian, Qu, Xiao, Xia, Kai, Wang, Fangtao, Zhang, Zichao, Yang, Muqing, Wu, Xiaocai, Gao, Renyuan, Yuan, Xiaoqi, Fang, Lin, Chen, Chunqiu, Yin, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066180/
https://www.ncbi.nlm.nih.gov/pubmed/37002201
http://dx.doi.org/10.1038/s41419-023-05756-6