Cargando…

The structural basis of the pH-homeostasis mediated by the Cl(−)/HCO(3)(−) exchanger, AE2

The cell maintains its intracellular pH in a narrow physiological range and disrupting the pH-homeostasis could cause dysfunctional metabolic states. Anion exchanger 2 (AE2) works at high cellular pH to catalyze the exchange between the intracellular HCO(3)(−) and extracellular Cl(−), thereby mainta...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qing, Jian, Liyan, Yao, Deqiang, Rao, Bing, Xia, Ying, Hu, Kexin, Li, Shaobai, Shen, Yafeng, Cao, Mi, Qin, An, Zhao, Jie, Cao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066210/
https://www.ncbi.nlm.nih.gov/pubmed/37002221
http://dx.doi.org/10.1038/s41467-023-37557-y