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The structural basis of the pH-homeostasis mediated by the Cl(−)/HCO(3)(−) exchanger, AE2
The cell maintains its intracellular pH in a narrow physiological range and disrupting the pH-homeostasis could cause dysfunctional metabolic states. Anion exchanger 2 (AE2) works at high cellular pH to catalyze the exchange between the intracellular HCO(3)(−) and extracellular Cl(−), thereby mainta...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066210/ https://www.ncbi.nlm.nih.gov/pubmed/37002221 http://dx.doi.org/10.1038/s41467-023-37557-y |