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An ultra-high-throughput screen for the evaluation of peptide HLA-Binder interactions

Peptide human leukocyte antigen (pHLA) targeting therapeutics like T-cell receptor based adoptive cell therapy or bispecific T cell engaging receptor molecules hold great promise for the treatment of cancer. Comprehensive pre-clinical screening of therapeutic candidates is important to ensure patien...

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Detalles Bibliográficos
Autores principales: Krämer, Stefan, Moritz, Andreas, Stehl, Luca, Hutt, Meike, Hofmann, Martin, Wagner, Claudia, Bunk, Sebastian, Maurer, Dominik, Roth, Günter, Wöhrle, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066226/
https://www.ncbi.nlm.nih.gov/pubmed/37002335
http://dx.doi.org/10.1038/s41598-023-32384-z