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Polygenic scores for psychiatric disorders in a diverse postmortem brain tissue cohort

A new era of human postmortem tissue research has emerged thanks to the development of ‘omics technologies that measure genes, proteins, and spatial parameters in unprecedented detail. Also newly possible is the ability to construct polygenic scores, individual-level metrics of genetic risk (also kn...

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Detalles Bibliográficos
Autores principales: Duncan, Laramie, Shen, Hanyang, Schulmann, Anton, Li, Tayden, Kolachana, Bhaskar, Mandal, Ajeet, Feng, Ningping, Auluck, Pavan, Marenco, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066241/
https://www.ncbi.nlm.nih.gov/pubmed/36694041
http://dx.doi.org/10.1038/s41386-022-01524-w