RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific

Thousands of RNA-binding proteins (RBPs) crosslink to cellular mRNA. Among these are numerous unconventional RBPs (ucRBPs)—proteins that associate with RNA but lack known RNA-binding domains (RBDs). The vast majority of ucRBPs have uncharacterized RNA-binding specificities. We analyzed 492 human ucR...

Descripción completa

Detalles Bibliográficos
Autores principales: Ray, Debashish, Laverty, Kaitlin U., Jolma, Arttu, Nie, Kate, Samson, Reuben, Pour, Sara E., Tam, Cyrus L., von Krosigk, Niklas, Nabeel-Shah, Syed, Albu, Mihai, Zheng, Hong, Perron, Gabrielle, Lee, Hyunmin, Najafabadi, Hamed, Blencowe, Benjamin, Greenblatt, Jack, Morris, Quaid, Hughes, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066285/
https://www.ncbi.nlm.nih.gov/pubmed/37002329
http://dx.doi.org/10.1038/s41598-023-32245-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066285/
https://www.ncbi.nlm.nih.gov/pubmed/37002329
http://dx.doi.org/10.1038/s41598-023-32245-9

Ejemplares similares