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Human IFT-A complex structures provide molecular insights into ciliary transport

Intraflagellar transport (IFT) complexes, IFT-A and IFT-B, form bidirectional trains that move along the axonemal microtubules and are essential for assembling and maintaining cilia. Mutations in IFT subunits lead to numerous ciliopathies involving multiple tissues. However, how IFT complexes assemb...

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Detalles Bibliográficos
Autores principales: Jiang, Meiqin, Palicharla, Vivek Reddy, Miller, Darcie, Hwang, Sun-Hee, Zhu, Hanwen, Hixson, Patricia, Mukhopadhyay, Saikat, Sun, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066299/
https://www.ncbi.nlm.nih.gov/pubmed/36775821
http://dx.doi.org/10.1038/s41422-023-00778-3