Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice

Perivascular adipocyte progenitor cells (APCs) can generate cold temperature-induced thermogenic beige adipocytes within white adipose tissue (WAT), an effect that could counteract excess fat mass and metabolic pathologies. Yet, the ability to generate beige adipocytes declines with age, creating a...

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Detalles Bibliográficos
Autores principales: Benvie, Abigail M., Lee, Derek, Steiner, Benjamin M., Xue, Siwen, Jiang, Yuwei, Berry, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066302/
https://www.ncbi.nlm.nih.gov/pubmed/37002214
http://dx.doi.org/10.1038/s41467-023-37386-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066302/
https://www.ncbi.nlm.nih.gov/pubmed/37002214
http://dx.doi.org/10.1038/s41467-023-37386-z

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