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The protease calpain2a limits innate immunity by targeting TRAF6 in teleost fish

TNF receptor-associated factor 6 (TRAF6) plays a key signal transduction role in both antibacterial and antiviral signaling pathways. However, the regulatory mechanisms of TRAF6 in lower vertebrates are less reported. In this study, we identify calpain2a, is a member of the calcium-dependent proteas...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Wang, Pengfei, Li, Qi, Yan, Xiaolong, Xu, Tianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066338/
https://www.ncbi.nlm.nih.gov/pubmed/37002312
http://dx.doi.org/10.1038/s42003-023-04711-7