Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder

Alcohol use disorders can be driven by negative reinforcement. Alterations of the microtubule cytoskeleton have been associated with mood regulation in the context of depression. Notably, MAP4343, a pregnenolone derivative known to promote tubulin assembly, has antidepressant properties. In the pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Macedo, Giovana C., Kreifeldt, Max, Goulding, Scott P., Okhuarobo, Agbonlahor, Sidhu, Harpreet, Contet, Candice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066354/
https://www.ncbi.nlm.nih.gov/pubmed/36670228
http://dx.doi.org/10.1038/s41386-023-01529-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066354/
https://www.ncbi.nlm.nih.gov/pubmed/36670228
http://dx.doi.org/10.1038/s41386-023-01529-z

Ejemplares similares