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Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder
Alcohol use disorders can be driven by negative reinforcement. Alterations of the microtubule cytoskeleton have been associated with mood regulation in the context of depression. Notably, MAP4343, a pregnenolone derivative known to promote tubulin assembly, has antidepressant properties. In the pres...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066354/ https://www.ncbi.nlm.nih.gov/pubmed/36670228 http://dx.doi.org/10.1038/s41386-023-01529-z |