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Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential

Nematode parasites of humans and livestock pose a significant burden to human health, economic development, and food security. Anthelmintic drug resistance is widespread among parasites of livestock and many nematode parasites of humans lack effective treatments. Here, we present a nitrophenyl-piper...

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Detalles Bibliográficos
Autores principales: Harrington, Sean, Pyche, Jacob, Burns, Andrew R., Spalholz, Tina, Ryan, Kaetlyn T., Baker, Rachel J., Ching, Justin, Rufener, Lucien, Lautens, Mark, Kulke, Daniel, Vernudachi, Alexandre, Zamanian, Mostafa, Deuther-Conrad, Winnie, Brust, Peter, Roy, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066365/
https://www.ncbi.nlm.nih.gov/pubmed/37002199
http://dx.doi.org/10.1038/s41467-023-37452-6