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Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma

Neutrophils are dynamic with their phenotype and function shaped by the microenvironment, such as the N1 antitumor and N2 pro-tumor states within the tumor microenvironment (TME), but its regulation remains undefined. Here we examine TGF-β1/Smad3 signaling in tumor-associated neutrophils (TANs) in n...

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Detalles Bibliográficos
Autores principales: Chung, Jeff Yat-Fai, Tang, Philip Chiu-Tsun, Chan, Max Kam-Kwan, Xue, Vivian Weiwen, Huang, Xiao-Ru, Ng, Calvin Sze-Hang, Zhang, Dongmei, Leung, Kam-Tong, Wong, Chun-Kwok, Lee, Tin-Lap, Lam, Eric W-F, Nikolic-Paterson, David J., To, Ka-Fai, Lan, Hui-Yao, Tang, Patrick Ming-Kuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066366/
https://www.ncbi.nlm.nih.gov/pubmed/37002229
http://dx.doi.org/10.1038/s41467-023-37515-8