Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients With Recurrent Glioblastoma: A Randomized Clinical Trial

IMPORTANCE: Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. OBJECTIVE: To evaluate the efficacy and safety of disulfiram and copper as add-on to alkylating chemotherapy in patients with recurre...

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Detalles Bibliográficos
Autores principales: Werlenius, Katja, Kinhult, Sara, Solheim, Tora Skeidsvoll, Magelssen, Henriette, Löfgren, David, Mudaisi, Munila, Hylin, Sofia, Bartek, Jiri, Strandéus, Michael, Lindskog, Magnus, Rashid, Havyan Bahroz, Carstam, Louise, Gulati, Sasha, Solheim, Ole, Salvesen, Øyvind, Jakola, Asgeir Store
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066460/
https://www.ncbi.nlm.nih.gov/pubmed/37000452
http://dx.doi.org/10.1001/jamanetworkopen.2023.4149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066460/
https://www.ncbi.nlm.nih.gov/pubmed/37000452
http://dx.doi.org/10.1001/jamanetworkopen.2023.4149

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