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Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis

Inhibition of heat shock protein 90 (Hsp90), a prominent molecular chaperone, effectively limits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection but little is known about any interaction between Hsp90 and SARS-CoV-2 proteins. Here, we systematically analyzed the effects of the...

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Detalles Bibliográficos
Autores principales: Zhao, Zhuangzhuang, Xu, Ling-Dong, Zhang, Fei, Liang, Qi-Zhang, Jiao, Yajuan, Shi, Fang-Shu, He, Biao, Xu, Pinglong, Huang, Yao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066589/
https://www.ncbi.nlm.nih.gov/pubmed/37011862
http://dx.doi.org/10.1016/j.jbc.2023.104668