DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops

Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic approaches and cellular analysis of specific mutants have uncovered factors potentially involved in R-loop homeostasis, we report a more open screening of factors whose depletion causes...

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Detalles Bibliográficos
Autores principales: Marchena-Cruz, Esther, Camino, Lola P., Bhandari, Jay, Silva, Sónia, Marqueta-Gracia, José Javier, Amdeen, Shahad A., Guillén-Mendoza, Cristina, García-Rubio, María L., Calderón-Montaño, José M., Xue, Xiaoyu, Luna, Rosa, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066596/
https://www.ncbi.nlm.nih.gov/pubmed/36827184
http://dx.doi.org/10.1016/j.celrep.2023.112148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066596/
https://www.ncbi.nlm.nih.gov/pubmed/36827184
http://dx.doi.org/10.1016/j.celrep.2023.112148

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