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Aerosolized Pulmonary Delivery of mRNA Constructs Attenuates Severity of Escherichia coli Pneumonia in the Rat

Acute respiratory distress syndrome (ARDS), a rapid onset inflammatory lung disease with no effective specific therapy, typically has pathogenic etiology termed pneumonia. In previous studies nuclear factor-κB (NF-κB) inhibitor α super-repressor (IκBα-SR) and extracellular superoxide dismutase 3 (SO...

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Detalles Bibliográficos
Autores principales: McCarthy, Sean D., Rohde, Christopher B., Angel, Matt, Masterson, Claire H., MacLoughlin, Ronan, Fandiño, Juan, González, Héctor E., Byrnes, Declan, Laffey, John G., O'Toole, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066785/
https://www.ncbi.nlm.nih.gov/pubmed/36811461
http://dx.doi.org/10.1089/nat.2022.0049