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Aerosolized Pulmonary Delivery of mRNA Constructs Attenuates Severity of Escherichia coli Pneumonia in the Rat

Acute respiratory distress syndrome (ARDS), a rapid onset inflammatory lung disease with no effective specific therapy, typically has pathogenic etiology termed pneumonia. In previous studies nuclear factor-κB (NF-κB) inhibitor α super-repressor (IκBα-SR) and extracellular superoxide dismutase 3 (SO...

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Detalles Bibliográficos
Autores principales:	McCarthy, Sean D., Rohde, Christopher B., Angel, Matt, Masterson, Claire H., MacLoughlin, Ronan, Fandiño, Juan, González, Héctor E., Byrnes, Declan, Laffey, John G., O'Toole, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2023
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066785/ https://www.ncbi.nlm.nih.gov/pubmed/36811461 http://dx.doi.org/10.1089/nat.2022.0049

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